Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 13/20 | 0.62 |
| ▸ | ITGB1 | P05556 | 13/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.38 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736051 | 0.91 | ITGB1 (0.54) | ITGA4ITGB1MAPTNPC1NFKB1 | |
| SCHEMBL4734982 | 0.86 | ITGA4 (0.49) | ITGA4ITGB1CYP3A4ITGB3ITGAV | |
| SCHEMBL4734738 | 0.81 | MAPT (0.59) | ITGA4ITGB1MAPTNPC1NFKB1 | |
| SCHEMBL4730913 | 0.79 | MAPT (0.67) | ITGA4ITGB1MAPTNPC1NFKB1 | |
| SCHEMBL4735069 | 0.78 | ITGB1 (0.41) | ITGA4ITGB1CYP3A4ITGB3ITGAV | |
| SCHEMBL5374019 | 0.77 | ITGB1 (1.00) | ITGA4ITGB1 | |
| SCHEMBL4736909 | 0.76 | MAPT (0.56) | ITGA4ITGB1MAPTNPC1NFKB1 | |
| SCHEMBL1414434 | 0.75 | MAPT (0.70) | ITGA4ITGB1MAPTNPC1NFKB1 | |
| SCHEMBL4733784 | 0.73 | MAPT (0.52) | ITGA4ITGB1MAPTNPC1NFKB1 | |
| SCHEMBL4733947 | 0.73 | MAPT (0.52) | MAPTNPC1NFKB1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | claimed |
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |