Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 8/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGAV | P06756 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735360 | 0.91 | ITGA4 (0.62) | ITGB1ITGA4MAPTNPC1RAB9A | |
| SCHEMBL4735069 | 0.87 | ITGB1 (0.41) | ITGB1ITGA4CYP3A4ITGB7ITGA5 | |
| SCHEMBL4733947 | 0.82 | MAPT (0.52) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL4733395 | 0.80 | MAPT (0.58) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL4734982 | 0.78 | ITGA4 (0.49) | ITGB1ITGA4CYP3A4ITGB7ITGA5 | |
| SCHEMBL4734738 | 0.73 | MAPT (0.59) | ITGB1ITGA4MAPTNPC1RAB9A | |
| SCHEMBL6797565 | 0.72 | MAPT (0.78) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL6797448 | 0.71 | LMNA (0.55) | MAPTNPC1RAB9AMAPK1NFKB1 | |
| SCHEMBL5374019 | 0.70 | ITGB1 (1.00) | ITGB1ITGA4 | |
| SCHEMBL1414433 | 0.70 | MAPT (0.62) | ITGB1ITGA4MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064823-A1 | BICYCLIC AND HETEROBICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES | UCB PHARMA, S.A. (BE) | 2008-06-05 | — | — | WO | disclosed |