Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735753 | 0.89 | HDAC4 (0.38) | HDAC4HDAC6KDM4EADORA2BHDAC3 | |
| SCHEMBL4739182 | 0.78 | HDAC4 (0.41) | HDAC4HDAC6KDM4EADORA2BHDAC3 | |
| SCHEMBL12286063 | 0.69 | HDAC4 (0.41) | HDAC4HDAC6KDM4EADORA2BHDAC3 | |
| SCHEMBL18501088 | 0.66 | HDAC4 (0.38) | HDAC4HDAC6KDM4EADORA2BHDAC3 | |
| SCHEMBL31376339 | 0.66 | KDM4E (0.46) | KDM4ELMNAALDH1A1GAATSHR | |
| SCHEMBL19543293 | 0.62 | KDM4E (0.42) | HDAC4HDAC6KDM4ELMNAALDH1A1 | |
| SCHEMBL19543295 | 0.61 | ADORA3 (0.47) | KDM4ELMNAALDH1A1GAATSHR | |
| SCHEMBL9726284 | 0.61 | KDM4E (0.62) | KDM4EADORA2BLMNAALDH1A1GAA | |
| SCHEMBL9225568 | 0.60 | HDAC4 (0.38) | HDAC4HDAC6KDM4EADORA2BHDAC3 | |
| SCHEMBL6731339 | 0.60 | KDM4E (0.64) | KDM4EIDO1LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075955-A2 | PROCESS FOR THE PREPARATION OF 1,4,5-TRISUBSTITUTED TRIAZOLES AND 3,4,5-TRISUBSTITUTED TRIAZOLES | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2008-06-26 | — | — | WO | disclosed |
| WO-2008075955-A2 | PROCESS FOR THE PREPARATION OF 1,4,5-TRISUBSTITUTED TRIAZOLES AND 3,4,5-TRISUBSTITUTED TRIAZOLES | STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN (NL) | 2008-06-26 | — | — | WO | disclosed |