Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4733674 | 0.86 | ALDH1A1 (0.52) | FASNKMT2AMGLLALDH1A1TP53 | |
| SCHEMBL14209216 | 0.86 | ALDH1A1 (0.52) | FASNMGLLALDH1A1CA12CA1 | |
| SCHEMBL4175647 | 0.85 | PARP10 (0.56) | FASNALDH1A1TP53HPGD | |
| SCHEMBL4191753 | 0.84 | PARP10 (0.58) | FASNKMT2AHSD11B1ALDH1A1TP53 | |
| SCHEMBL4197739 | 0.84 | FASN (0.61) | FASNMGLLALDH1A1TP53HPGD | |
| SCHEMBL16799271 | 0.84 | HPGD (0.50) | FASNALDH1A1TSHRTP53HPGD | |
| SCHEMBL4735211 | 0.83 | CA12 (0.58) | FASNHSD11B1ALDH1A1HTTTSHR | |
| SCHEMBL4183575 | 0.83 | CA12 (0.53) | FASNALDH1A1CYP3A4CA12CA1 | |
| SCHEMBL4731334 | 0.82 | FASN (0.63) | FASNKMT2AHSD11B1ALDH1A1GAA | |
| SCHEMBL4735697 | 0.82 | LMNA (0.51) | FASNHSD11B1ALDH1A1TP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008059214-A1 | BISAMLDE DERIVATIVES AND USE THEREOF AS FATTY ACID SYNTHASE INHIBITORS | ASTRAZENECA AB (SE) | 2008-05-22 | — | — | WO | disclosed |