Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP5 | P45974 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784947 | 0.87 | GFER (0.50) | RAB9AGFERGAAKMT2ANPC1 | |
| SCHEMBL4799793 | 0.82 | RAB9A (0.59) | RAB9AGFERGAAKMT2ANPC1 | |
| SCHEMBL4740360 | 0.80 | ALOX15 (0.48) | RAB9AGFERGAAKMT2AHPGD | |
| SCHEMBL4740852 | 0.79 | RAB9A (0.51) | RAB9AGFERGAAKMT2ANPC1 | |
| SCHEMBL4740458 | 0.75 | HTT (0.47) | GFERKMT2AMAPTKDM4EMEN1 | |
| SCHEMBL4786062 | 0.72 | RAB9A (0.50) | RAB9AGFERGAAKMT2ANPC1 | |
| SCHEMBL4497139 | 0.71 | ALDH1A1 (0.43) | RAB9AGAAKMT2AHPGDMAPT | |
| SCHEMBL259629 | 0.70 | RAB9A (0.59) | RAB9AGFERGAAKMT2ANPC1 | |
| SCHEMBL3159586 | 0.70 | RAB9A (0.59) | RAB9AGFERGAAKMT2ANPC1 | |
| SCHEMBL4785588 | 0.70 | GFER (0.47) | RAB9AGFERGAAKMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |