Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740458 | 0.81 | HTT (0.47) | ALOX15KMT2AMAPTKDM4EHTT | |
| SCHEMBL4736668 | 0.80 | RAB9A (0.51) | KMT2AGAAALDH1A1MAPTKDM4E | |
| SCHEMBL4784947 | 0.76 | GFER (0.50) | KMT2AGAAALDH1A1MAPTKDM4E | |
| SCHEMBL4783050 | 0.76 | PTGS2 (0.53) | KMT2AHSD17B10ALDH1A1MAPTHTT | |
| SCHEMBL4799793 | 0.72 | RAB9A (0.59) | KMT2AGAAALDH1A1MAPTKDM4E | |
| SCHEMBL11623108 | 0.69 | ALDH1A1 (0.51) | ALOX15KMT2AHSD17B10GAAALDH1A1 | |
| SCHEMBL4740852 | 0.69 | RAB9A (0.51) | KMT2AGAAALDH1A1MAPTKDM4E | |
| SCHEMBL4738664 | 0.69 | KMT2A (0.50) | KMT2AHSD17B10ALDH1A1MAPTKDM4E | |
| SCHEMBL9036962 | 0.68 | GAA (0.54) | ALOX15KMT2AHSD17B10GAAALDH1A1 | |
| SCHEMBL4913725 | 0.67 | TSHR (0.67) | ALOX15KMT2AHSD17B10GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |