Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4808038 | 0.91 | MAPT (0.48) | ALDH1A1EPHX2CYP3A4CYP2C19LMNA | |
| SCHEMBL4741684 | 0.90 | ALDH1A1 (0.49) | ALDH1A1EPHX2CYP3A4CYP2C19LMNA | |
| SCHEMBL4785880 | 0.89 | CYP3A4 (0.46) | CYP3A4CYP2C19LMNAPKMSMN1; SMN2 | |
| SCHEMBL4736649 | 0.87 | CYP3A4 (0.50) | ALDH1A1EPHX2CYP3A4CYP2C19LMNA | |
| SCHEMBL4740746 | 0.87 | CYP3A4 (0.50) | ALDH1A1EPHX2CYP3A4CYP2C19LMNA | |
| SCHEMBL4737578 | 0.87 | EPHX2 (0.49) | ALDH1A1EPHX2CYP2C19LMNACNR2 | |
| SCHEMBL4739746 | 0.87 | HDAC3 (0.52) | CYP3A4CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL4740922 | 0.87 | CYP19A1 (0.43) | ALDH1A1CYP3A4CYP2C19LMNACYP19A1 | |
| SCHEMBL4738916 | 0.87 | HDAC3 (0.52) | CYP3A4CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL4736709 | 0.86 | LMNA (0.57) | ALDH1A1CYP3A4CYP2C19LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |