Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740138 | 0.91 | L3MBTL1 (0.46) | EPHX2CYP19A1LMNATDP1CNR2 | |
| SCHEMBL4736673 | 0.87 | ALDH1A1 (0.50) | EPHX2CYP19A1LMNACNR2ALDH1A1 | |
| SCHEMBL4738916 | 0.87 | HDAC3 (0.52) | LMNAATAD2HSD11B1CYP2C19SMN1; SMN2 | |
| SCHEMBL4739746 | 0.87 | HDAC3 (0.52) | LMNAATAD2HSD11B1CYP2C19SMN1; SMN2 | |
| SCHEMBL4740922 | 0.87 | CYP19A1 (0.43) | CYP19A1LMNAHSD11B1GAAALDH1A1 | |
| SCHEMBL4736709 | 0.86 | LMNA (0.57) | LMNAALDH1A1HTTCYP2C19SMN1; SMN2 | |
| SCHEMBL4737593 | 0.86 | LMNA (0.57) | LMNAALDH1A1HTTCYP2C19SMN1; SMN2 | |
| SCHEMBL4786375 | 0.85 | HSD11B1 (0.62) | LMNAATAD2HSD11B1GAAALDH1A1 | |
| SCHEMBL4740145 | 0.85 | MAPT (0.49) | CYP19A1TDP1CNR2GAAMITF | |
| SCHEMBL4782830 | 0.85 | HSD11B1 (0.62) | LMNAATAD2HSD11B1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |