Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737934 | 0.90 | L3MBTL1 (0.76) | KDM4EL3MBTL1LMNACASP3SENP8 | |
| SCHEMBL4734529 | 0.88 | KDM4E (0.64) | KDM4EL3MBTL1LMNACASP3SENP8 | |
| SCHEMBL7435098 | 0.79 | L3MBTL1 (0.77) | KDM4EL3MBTL1LMNAALDH1A1RAB9A | |
| SCHEMBL4908172 | 0.78 | ALDH1A1 (0.84) | KDM4ELMNAALDH1A1KMT2ARAB9A | |
| SCHEMBL9360758 | 0.77 | KMT2A (0.73) | KDM4EL3MBTL1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL4734498 | 0.77 | LMNA (0.78) | KDM4EL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL4732827 | 0.77 | L3MBTL1 (1.00) | KDM4EL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL20545056 | 0.76 | RAB9A (0.67) | KDM4EL3MBTL1LMNACASP3SENP8 | |
| SCHEMBL7439819 | 0.76 | LMNA (0.73) | KDM4EL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL7870786 | 0.76 | ALDH1A1 (0.66) | LMNAALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | claimed |
| WO-2008069611-A1 | N-PHENYLAMIDE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF, AND COMPOSITION FOR PREVENTING OR TREATING ISCHEMIC DISEASES COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-06-12 | — | — | WO | disclosed |