Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4739901 | 0.80 | HSD11B1 (0.61) | HSD11B1ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL4786375 | 0.79 | HSD11B1 (0.62) | HSD11B1ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL4782830 | 0.79 | HSD11B1 (0.62) | HSD11B1ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL4736702 | 0.78 | HSD11B1 (0.58) | HSD11B1ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL4736614 | 0.78 | HSD11B1 (0.66) | HSD11B1ALDH1A1LMNATSHRMEN1 | |
| SCHEMBL4736653 | 0.78 | HSD11B1 (0.55) | HSD11B1ALDH1A1GAAHDAC3HDAC4 | |
| SCHEMBL4740132 | 0.77 | HSD11B1 (0.55) | HSD11B1LMNAMEN1KMT2ATP53 | |
| SCHEMBL4736817 | 0.77 | HTT (0.46) | HSD11B1ALDH1A1LMNATSHRKMT2A | |
| SCHEMBL4740379 | 0.77 | HSD11B1 (0.56) | HSD11B1ALDH1A1LMNATSHRMAPK1 | |
| SCHEMBL4912062 | 0.77 | HSD11B1 (0.54) | HSD11B1ALDH1A1LMNANPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |