Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741276 | 0.89 | TSHR (0.41) | HTTTSHRCCR1HSD11B1LMNA | |
| SCHEMBL4740126 | 0.82 | CCR1 (0.44) | HTTTSHRCCR1LMNAPOLB | |
| SCHEMBL4736814 | 0.79 | TSHR (0.47) | TSHRCCR1HSD11B1LMNAKMT2A | |
| SCHEMBL4787140 | 0.79 | POLB (0.51) | CYP3A4ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL4741083 | 0.78 | TSHR (0.58) | TSHRALDH1A1CCR1HSD11B1LMNA | |
| SCHEMBL4740463 | 0.77 | TSHR (0.56) | TSHRALDH1A1CCR1HSD11B1LMNA | |
| SCHEMBL4736733 | 0.77 | HSD11B1 (0.51) | HTTTSHRALDH1A1HSD11B1LMNA | |
| SCHEMBL4740080 | 0.77 | GAA (0.47) | HTTALDH1A1LMNAPOLBMAPT | |
| Potassium Ion SCHEMBL4740462 | 0.76 | TSHR (0.55) | HTTTSHRALDH1A1CCR1HSD11B1 | |
| SCHEMBL4738255 | 0.76 | TSHR (0.58) | TSHRALDH1A1CCR1HSD11B1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |