Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4735156 | 0.83 | KCNH2 (0.39) | L3MBTL1KDM4ELMNAMAPTHTT | |
| SCHEMBL3071006 | 0.81 | CACNA1H (0.47) | CACNA1HRAB9AAOC3KDM4ELMNA | |
| SCHEMBL4736030 | 0.81 | CACNA1H (0.47) | CACNA1HAOC3KDM4ECNR2MAPK14 | |
| SCHEMBL4734213 | 0.80 | LMNA (0.54) | CACNA1HL3MBTL1NPC1RAB9AKDM4E | |
| SCHEMBL4803555 | 0.79 | ME2 (0.39) | L3MBTL1KDM4ELMNAMAPT | |
| SCHEMBL4733787 | 0.79 | KMT2A (0.48) | CACNA1HNPC1RAB9AKDM4ELMNA | |
| SCHEMBL3821700 | 0.78 | CNR2 (0.49) | CACNA1HAOC3NPSR1CNR2MAPK14 | |
| SCHEMBL3815393 | 0.78 | CACNA1H (0.45) | CACNA1HAOC3KDM4ELMNANPSR1 | |
| SCHEMBL3064331 | 0.78 | CACNA1H (0.45) | CACNA1HAOC3CNR2LTB4R2 | |
| SCHEMBL4738911 | 0.78 | CACNA1H (0.40) | CACNA1HL3MBTL1NPC1AOC3CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |