Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ME2 | P23368 | 1/20 | 0.39 |
| ▸ | ME1 | P48163 | 1/20 | 0.39 |
| ▸ | ME3 | Q16798 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738708 | 0.91 | ALDH1A1 (0.46) | SMN1; SMN2KDM4EALDH1A1TSHRHTR1A | |
| SCHEMBL4734880 | 0.89 | MEN1 (0.37) | ME2ME1ME3MAPTSMN1; SMN2 | |
| SCHEMBL4734210 | 0.88 | HTR1A (0.47) | ME2ME1ME3KDM4EALDH1A1 | |
| SCHEMBL4735156 | 0.80 | KCNH2 (0.39) | MAPTKDM4EALDH1A1TSHRLMNA | |
| SCHEMBL4736795 | 0.79 | CACNA1H (0.43) | MAPTKDM4ELMNAL3MBTL1 | |
| SCHEMBL3830332 | 0.79 | MEN1 (0.45) | ME2ME1ME3MAPTSMN1; SMN2 | |
| SCHEMBL4737954 | 0.79 | KDM4E (0.45) | ME2ME1ME3SMN1; SMN2KDM4E | |
| SCHEMBL4734783 | 0.79 | OPRM1 (0.40) | ME2ME1ME3MAPTSMN1; SMN2 | |
| SCHEMBL4738913 | 0.79 | MAOB (0.40) | ME2ME1ME3MAPTSMN1; SMN2 | |
| SCHEMBL4739792 | 0.78 | LMNA (0.49) | MAPTKDM4EALDH1A1TSHROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008073461-A2 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | claimed |