Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3811734 | 0.95 | SIGMAR1 (0.41) | CACNA1GCACNA1HSIGMAR1OPRM1OPRD1 | |
| SCHEMBL3667025 | 0.89 | CACNA1G (0.36) | CACNA1GCACNA1HSIGMAR1OPRM1OPRD1 | |
| SCHEMBL3721849 | 0.80 | CACNA1G (0.42) | CACNA1GCACNA1HCYP2D6CYP3A4C5AR1 | |
| Biotin SCHEMBL3666882 | 0.80 | CA12 (0.39) | — | |
| SCHEMBL3811730 | 0.80 | SIGMAR1 (0.36) | CACNA1GCACNA1HSIGMAR1OPRM1OPRD1 | |
| SCHEMBL1832947 | 0.78 | CACNA1G (0.38) | CACNA1GCACNA1HOPRM1CYP3A4 | |
| SCHEMBL4802758 | 0.77 | CACNA1G (0.40) | CACNA1GCACNA1HCYP2D6CYP3A4TACR1 | |
| SCHEMBL1838526 | 0.77 | KDM4E (0.43) | OPRM1OPRK1OPRL1CYP2D6 | |
| SCHEMBL4784349 | 0.76 | CCR5 (0.40) | — | |
| SCHEMBL13980393 | 0.75 | CACNA1G (0.44) | CACNA1GCACNA1HSIGMAR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |