Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DBH | P09172 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736170 | 0.83 | KMT2A (0.58) | RAB9AKMT2AMEN1KDM4ERECQL | |
| SCHEMBL4739765 | 0.82 | RAB9A (0.46) | RAB9AKMT2AMEN1KDM4ERECQL | |
| SCHEMBL4735266 | 0.79 | DBH (0.56) | RAB9AKMT2AMEN1KDM4ERECQL | |
| SCHEMBL4737872 | 0.77 | KMT2A (0.51) | RAB9AKMT2AMEN1KDM4ERECQL | |
| SCHEMBL4739836 | 0.77 | KMT2A (0.49) | RAB9AKMT2AMEN1KDM4ERECQL | |
| SCHEMBL9473724 | 0.75 | SLC22A12 (0.47) | RAB9AKMT2AMEN1SMN1; SMN2LMNA | |
| SCHEMBL4738830 | 0.73 | KMT2A (0.61) | RAB9AKMT2AMEN1KDM4ERECQL | |
| SCHEMBL4738142 | 0.73 | CYP11B1 (0.50) | RAB9AKMT2AMEN1KDM4ERECQL | |
| SCHEMBL9372580 | 0.72 | RAB9A (0.50) | RAB9AKMT2AMEN1KDM4ERECQL | |
| SCHEMBL4739723 | 0.72 | RAB9A (0.45) | RAB9AKMT2AMEN1KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |