Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 6/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4784803 | 0.87 | CYP11B1 (0.53) | CYP11B1CYP11B2CYP19A1KMT2AHDAC8 | |
| SCHEMBL4736170 | 0.85 | KMT2A (0.58) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4737872 | 0.82 | KMT2A (0.51) | KMT2AHDAC8HDAC6KDM4EMEN1 | |
| SCHEMBL4739836 | 0.82 | KMT2A (0.49) | CYP11B1CYP11B2KMT2AHDAC8HDAC6 | |
| SCHEMBL4738830 | 0.78 | KMT2A (0.61) | CYP11B1CYP11B2KMT2AKDM4EMEN1 | |
| SCHEMBL4740266 | 0.73 | RAB9A (0.71) | KMT2AKDM4EMEN1RXFP1RAB9A | |
| SCHEMBL4738141 | 0.73 | RAB9A (0.46) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4740547 | 0.73 | DBH (0.53) | KMT2AKDM4EMEN1RECQLRXFP1 | |
| SCHEMBL4739765 | 0.70 | RAB9A (0.46) | KMT2AHDAC8HDAC6KDM4EMEN1 | |
| SCHEMBL4739723 | 0.69 | RAB9A (0.45) | KMT2AKDM4EMEN1RECQLRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |