Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736170 | 0.79 | KMT2A (0.58) | RAB9AKDM4EKMT2AMEN1RECQL | |
| SCHEMBL7012155 | 0.74 | UPP1 (0.44) | KDM4EKMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL4739836 | 0.72 | KMT2A (0.49) | RAB9AKDM4EKMT2AMEN1RECQL | |
| SCHEMBL4737872 | 0.72 | KMT2A (0.51) | RAB9AKDM4EKMT2AMEN1RECQL | |
| SCHEMBL4738141 | 0.72 | RAB9A (0.46) | RAB9AKDM4EKMT2AMEN1RECQL | |
| SCHEMBL4739765 | 0.72 | RAB9A (0.46) | RAB9AKDM4EKMT2AMEN1RECQL | |
| SCHEMBL9372580 | 0.71 | RAB9A (0.50) | RAB9AKDM4EKMT2AMEN1RECQL | |
| SCHEMBL4735233 | 0.71 | KMT2A (0.57) | RAB9AKDM4EKMT2AMEN1RECQL | |
| SCHEMBL4786062 | 0.70 | RAB9A (0.50) | RAB9AKDM4EKMT2AMEN1RECQL | |
| SCHEMBL4738830 | 0.69 | KMT2A (0.61) | RAB9AKDM4EKMT2AMEN1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |