Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736170 | 0.85 | KMT2A (0.58) | KMT2AGAARAB9AHPGDNPC1 | |
| SCHEMBL4739836 | 0.82 | KMT2A (0.49) | KMT2AGAARAB9ANPC1MEN1 | |
| SCHEMBL4737872 | 0.82 | KMT2A (0.51) | KMT2AGAARAB9AHPGDNPC1 | |
| SCHEMBL1597131 | 0.80 | LTA4H (0.51) | KMT2AGAARAB9AHPGDNPC1 | |
| SCHEMBL4738142 | 0.78 | CYP11B1 (0.50) | KMT2AGAARAB9AMEN1KDM4E | |
| SCHEMBL4735266 | 0.78 | DBH (0.56) | KMT2AGAARAB9AHPGDNPC1 | |
| SCHEMBL4738141 | 0.73 | RAB9A (0.46) | KMT2AGAARAB9AHPGDNPC1 | |
| SCHEMBL4787183 | 0.73 | KMT2A (0.89) | KMT2AGAARAB9AHPGDNPC1 | |
| SCHEMBL4740547 | 0.73 | DBH (0.53) | KMT2AGAARAB9ANPC1MEN1 | |
| SCHEMBL4785588 | 0.71 | GFER (0.47) | KMT2AGAARAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |