SCHEMBL4738176

SCHEMBL4738176

O=C1C[C@@H](O)[C@H](O)[C@@H](CO)O1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.48
GBA1 P04062 1/20 0.48
PRKCA P17252 6/20 0.42
PTPN1 P18031 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.34
THRB P10828 1/20 0.34
ALOX15 P16050 1/20 0.34
OGA O60502 1/20 0.33
PRKACA P17612 1/20 0.33
AKT1 P31749 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18857527 1.00 LMNA (0.48) LMNAGBA1PRKCAPTPN1SMN1; SMN2
SCHEMBL20832189 1.00 LMNA (0.48) LMNAGBA1PRKCAPTPN1SMN1; SMN2
SCHEMBL9838955 1.00 LMNA (0.48) LMNAGBA1PRKCAPTPN1SMN1; SMN2
SCHEMBL3394583 0.87
SCHEMBL22601799 0.87
SCHEMBL24114686 0.87
SCHEMBL9130905 0.87
SCHEMBL9131631 0.87
SCHEMBL4378652 0.87
SCHEMBL3390444 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1991002741-A1 SUGAR ALCOHOL DERIVATIVES, A PROCESS FOR PREPARING 3-DEOXY-2-OCTULOSONIC ACID AND 3-DEOXY-2-HEPTULOSONIC ACID COMPOUNDS AND DERIVATIVES RIJKSUNIVERSITEIT TE LEIDEN (NL) 1991-03-07 WO claimed
US-11696891-B2 Glucono delta-lactone for treatment of vaginal fungal infections GEDEA BIOTECH AB (SE) 2023-07-11 US disclosed
US-20220031640-A1 FORMULATIONS FOR EPIDURAL REPAIR CLARIDEI LABORATORIES, INC. 2022-02-03 US disclosed
WO-2021226330-A1 AGENTS TO PREVENT TISSUE DAMAGE FROM CLOSTRIDIUM DIFFICILE INFECTIONS BY INHIBITION OF THE GUT-DAMAGING BACTERIAL TOXINS TCDA AND TCDB ALBERT EINSTEIN COLLEGE OF MEDICINE (US) 2021-11-11 WO disclosed
US-11135184-B2 Formulations for epidermal repair CLARIDEI LABORATORIES, INC. (US) 2021-10-05 US disclosed
US-20210212937-A1 GLUCONO DELTA-LACTONE FOR TREATMENT OF VAGINAL FUNGAL INFECTIONS GEDEA BIOTECH AB (SE) 2021-07-15 US disclosed
US-10993907-B2 Glucono delta-lactone for treatment of vaginal fungal infections GEDEA BIOTECH AB (SE) 2021-05-04 US disclosed
US-10918652-B2 Compositions for the treatment of dermatological diseases and disorders CLARIDEI LABORATORIES, INC. (US) 2021-02-16 US disclosed
US-20200253925-A1 GLUCONIC ACID DERIVATIVES FOR USE IN THE TREATMENT AND/OR PREVENTION OF MICROBIAL INFECTIONS GEDEA BIOTECH AB (SE) 2020-08-13 US disclosed
US-20190336517-A1 COMPOSITIONS FOR THE TREATMENT OF DERMATOLOGICAL DISEASES AND DISORDERS CLARIDEI LABORATORIES, INC. (US) 2019-11-07 US disclosed
US-20190090527-A1 EDIBLE CANNABINOID COMPOSITIONS WILMINGTON TRUST, NATIONAL ASSOCIATION, AS COLLATERAL AGENT 2019-03-28 US disclosed
WO-2017174731-A1 GLUCONO DELTA-LACTONE FOR TREATMENT OF VAGINAL FUNGAL INFECTIONS GEDEA BIOTECH AB (SE) 2017-10-12 WO disclosed
US-20170173056-A1 COMPOSITIONS FOR THE TREATMENT OF DERMATOLOGICAL DISEASES AND DISORDERS CLARIDEI LABORATORIES, INC. 2017-06-22 US disclosed
WO-2008086783-A2 PLATINUM COMPLEX DEMEDTS ARNOUD (DE) 2008-07-24 WO disclosed
US-6562514-B1 Stabilized vanadium electrolyte solutions for all-vanadium redox cells and batteries PINNACLE VRB LIMITED (AU) 2003-05-13 US disclosed
US-6468688-B2 CHARGING, DISCHARGING EFFICIENCY; VANADIUM ELECTROLYTE PINNACLE VRB LIMITED (AU) 2002-10-22 US disclosed
US-20010028977-A1 Charging, discharging efficiency; vanadium electrolyte JD HOLDING INC. (KY) 2001-10-11 US disclosed
US-6143443-A ALL-VANADIUM REDOX BATTERY, COMPRISING THE STABILIZED ELECTROLYTE PINNACLE ARB LIMITED (AU) 2000-11-07 US disclosed
EP-0829104-A1 HIGH ENERGY DENSITY VANADIUM ELECTROLYTE SOLUTIONS, METHODS OF PREPARATION THEREOF AND ALL-VANADIUM REDOX CELLS AND BATTERIES CONTAINING HIGH ENERGY VANADIUM ELECTROLYTE SOLUTIONS UNISEARCH LIMITED (AU) 1998-03-18 EP disclosed
WO-1991002741-A1 SUGAR ALCOHOL DERIVATIVES, A PROCESS FOR PREPARING 3-DEOXY-2-OCTULOSONIC ACID AND 3-DEOXY-2-HEPTULOSONIC ACID COMPOUNDS AND DERIVATIVES RIJKSUNIVERSITEIT TE LEIDEN (NL) 1991-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11696891-B2 Glucono delta-lactone for treatment of vaginal fungal infections CYP51A1, HSD17B11, UGGT1 LMNA 3583/4885GBA1 57/4885PRKCA 599/4885
US-10993907-B2 Glucono delta-lactone for treatment of vaginal fungal infections CYP51A1, HSD17B11, UGGT1 LMNA 3583/4885GBA1 57/4885PRKCA 599/4885
US-20210212937-A1 GLUCONO DELTA-LACTONE FOR TREATMENT OF VAGINAL FUNGAL INFECTIONS CYP51A1, HSD17B11, UGGT1 LMNA 3583/4885GBA1 57/4885PRKCA 599/4885
US-20170173056-A1 COMPOSITIONS FOR THE TREATMENT OF DERMATOLOGICAL DISEASES AND DISORDERS CUTA, TYR, DSG1 LMNA 3610/4885GBA1 324/4885PRKCA 2171/4885
US-10918652-B2 Compositions for the treatment of dermatological diseases and disorders CUTA, TYR, DSG1 LMNA 3610/4885GBA1 324/4885PRKCA 2171/4885
US-20220031640-A1 FORMULATIONS FOR EPIDURAL REPAIR CUTA, EPHB1, EPHB2 LMNA 1173/4885GBA1 1405/4885PRKCA 4741/4885
US-20200253925-A1 GLUCONIC ACID DERIVATIVES FOR USE IN THE TREATMENT AND/OR PREVENTION OF MICROBIAL INFECTIONS FUT6, UGGT1, MGAM LMNA 4638/4885GBA1 61/4885PRKCA 2067/4885
US-20190336517-A1 COMPOSITIONS FOR THE TREATMENT OF DERMATOLOGICAL DISEASES AND DISORDERS CUTA, TYR, DSG1 LMNA 3610/4885GBA1 324/4885PRKCA 2171/4885
US-11135184-B2 Formulations for epidermal repair KRT18, CUTA, DSG1 LMNA 2396/4885GBA1 3094/4885PRKCA 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.