Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014349 | 0.81 | KDM4E (0.42) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL9541523 | 0.80 | MTNR1A (0.43) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL7417657 | 0.80 | MTNR1A (0.43) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL2020254 | 0.79 | CA4 (0.43) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL10816359 | 0.78 | LTA4H (0.45) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL1453272 | 0.78 | CA4 (0.48) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL542873 | 0.78 | KDM4E (0.50) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL12394 | 0.78 | KMT2A (0.54) | MTNR1AMTNR1BGAACYP1A2CYP2C9 | |
| SCHEMBL6516593 | 0.77 | ACHE (0.46) | KMT2ALMNAMEN1ALDH1A1TSHR | |
| SCHEMBL5697814 | 0.77 | CA1 (0.55) | MTNR1AMTNR1BGAAPKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1078 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113620945-A | RET inhibitor, pharmaceutical composition thereof and application thereof in medicines | 广东东阳光药业有限公司 | 2021-11-09 | — | — | CN | claimed |
| CN-113620944-A | Novel RET inhibitors, pharmaceutical compositions thereof and uses thereof | 广东东阳光药业有限公司 | 2021-11-09 | — | — | CN | claimed |
| WO-2013175281-A1 | USE OF SUBSTITUTED 2-PHENYL-3H-QUINAZOLIN-4-ONES AND ANALOGS FOR INHIBITING BROMODOMAIN AND EXTRA TERMINAL DOMAIN (BET) PROTEINS | RVX THERAPEUTICS INC. (CA) | 2013-11-28 | — | — | WO | claimed |
| US-20130281399-A1 | TREATMENT OF DISEASES BY EPIGENETIC REGULATION | RVX THERAPEUTICS INC. (CA) | 2013-10-24 | — | — | US | claimed |
| WO-2012176123-A1 | 3 - IMIDAZOLYL- INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2012-12-27 | — | — | WO | claimed |
| EP-2408454-A2 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2012-01-25 | — | — | EP | claimed |
| US-7829585-B2 | Antifungal agent containing pyridine derivative | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-11-09 | — | — | US | claimed |
| WO-2010106436-A2 | NOVEL ANTI-INFLAMMATORY AGENTS | RESVERLOGIX CORP. (CA) | 2010-09-23 | — | — | WO | claimed |
| WO-2009140215-A2 | METHOD FOR TREATING DRUG-RESISTANT BACTERIAL AND OTHER INFECTIONS WITH CLIOQUINOL, PHANQUINONE, AND RELATED COMPOUNDS | GERAGHTY, ERIN (US) | 2009-11-19 | — | — | WO | claimed |
| US-20090227585-A1 | SUBSTITUTED N-HETEROCYCLE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2009-09-10 | — | — | US | claimed |
| EP-0023601-A1 | Process for dyeing and printing textile material containing cellulose | BASF Aktiengesellschaft (DE) | 1981-02-11 | — | — | EP | claimed |
| EP-0023315-A1 | Processes for dyeing and printing textile material containing cellulose | BASF Aktiengesellschaft (DE) | 1981-02-04 | — | — | EP | claimed |
| EP-0023309-A1 | Disazo dyestuffs of the aminopyridine or aminopyrimidine series and their use in dyeing textile material containing cellulose | BASF Aktiengesellschaft (DE) | 1981-02-04 | — | — | EP | claimed |
| US-4239894-A | DYES FOR SYNTHETIC AND NATURAL FIBERS | BASF AKTIENGESELLSCHAFT (DE) | 1980-12-16 | — | — | US | claimed |
| EP-0009191-A1 | Water-insoluble disazodyestuffs, their preparation and application | CASSELLA Aktiengesellschaft (DE) | 1980-04-02 | — | — | EP | claimed |
| US-4140684-A | FOR POLYESTERS, POLYAMIDES, AND CELLULOSE ACETATES | FIDELITY UNION TRUST COMPANY, EXECUTIVE TRUSTEE UNDER THE SANDOZ TRUST (US) | 1979-02-20 | — | — | US | claimed |
| US-4128545-A | DISPERSE, POLYESTER | BASF AKTIENGESELLSCHAFT (DE) | 1978-12-05 | — | — | US | claimed |
| US-4113720-A | Disperse azo dye with diaminopyrimidine coupling component | BASF AKTIENGESELLSCHAFT (DE) | 1978-09-12 | — | — | US | claimed |
| US-4011320-A | PESTICIDES, FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1977-03-08 | — | — | US | claimed |
| US-3950321-A | POLYESTERS | BASF AKTIENGESELLSCHAFT (DT) | 1976-04-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130281399-A1 | TREATMENT OF DISEASES BY EPIGENETIC REGULATION | PHKB, BAZ2A, EP300 | MTNR1A 874/4885MTNR1B 1337/4885GAA 1418/4885 |
| US-20090227585-A1 | SUBSTITUTED N-HETEROCYCLE DERIVATIVES AND METHODS OF THEIR USE | MAOA, MAOB, SDHA | MTNR1A 279/4885MTNR1B 397/4885GAA 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.