Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740459 | 0.92 | ALDH1A1 (0.51) | RAB9AGAAMAPTALDH1A1LMNA | |
| SCHEMBL4741097 | 0.92 | ALDH1A1 (0.51) | RAB9AGAAMAPTALDH1A1LMNA | |
| SCHEMBL4740197 | 0.89 | LMNA (0.50) | RAB9AMAPTALDH1A1LMNAMEN1 | |
| SCHEMBL4740901 | 0.89 | CYP19A1 (0.58) | RAB9AGAAHTTMAPTALDH1A1 | |
| SCHEMBL4740383 | 0.88 | SMN1; SMN2 (0.58) | RAB9AGAAHTTALDH1A1LMNA | |
| SCHEMBL4739860 | 0.86 | ALDH1A1 (0.55) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL4738964 | 0.86 | POLB (0.51) | GAAHTTMAPTALDH1A1LMNA | |
| SCHEMBL4741708 | 0.85 | ALDH1A1 (0.56) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL4740191 | 0.84 | ALDH1A1 (0.55) | GAAHTTMAPTALDH1A1LMNA | |
| SCHEMBL4786793 | 0.84 | CNR1 (0.47) | MAPTALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | disclosed |