Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.74 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.74 |
| ▸ | TGM2 | P21980 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.64 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.64 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740155 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TGM2MAPTLMNATHRB | |
| SCHEMBL4740156 | 0.85 | ALDH1A1 (1.00) | ALDH1A1TGM2MAPTLMNATHRB | |
| SCHEMBL4147796 | 0.84 | MMP1 (0.63) | MTNR1AMTNR1BALDH1A1TGM2MAPT | |
| SCHEMBL19142994 | 0.84 | MMP1 (0.63) | MTNR1AMTNR1BALDH1A1TGM2MAPT | |
| SCHEMBL4147799 | 0.84 | MMP1 (0.63) | MTNR1AMTNR1BALDH1A1TGM2MAPT | |
| SCHEMBL24262378 | 0.81 | MTNR1A (0.71) | MTNR1AMTNR1BALDH1A1TGM2MAPT | |
| SCHEMBL19501011 | 0.81 | SMN1; SMN2 (0.61) | MTNR1AMTNR1BALDH1A1TGM2MAPT | |
| SCHEMBL262594 | 0.81 | MAPT (0.59) | MTNR1AMTNR1BALDH1A1TGM2MAPT | |
| SCHEMBL262593 | 0.81 | MAPT (0.59) | MTNR1AMTNR1BALDH1A1TGM2MAPT | |
| SCHEMBL9017578 | 0.80 | TGM2 (1.00) | ALDH1A1TGM2MAPTLMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200062696-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RETICULON 4 | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200062696-A1 | COMPOSITIONS AND METHODS FOR INHIBITING RETICULON 4 | RTN4, RTN3, RCN1 | MTNR1A 4352/4885MTNR1B 4359/4885ALDH1A1 4014/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.