Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737066 | 0.99 | PTGS2 (0.49) | PTGS2MEN1RAB9AKMT2AGRIN2B | |
| SCHEMBL4783050 | 0.88 | PTGS2 (0.53) | PTGS2MEN1KMT2AGRIN2BALDH1A1 | |
| SCHEMBL4786062 | 0.81 | RAB9A (0.50) | PTGS2MEN1RAB9AKMT2AALDH1A1 | |
| SCHEMBL4785588 | 0.75 | GFER (0.47) | MEN1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL4783037 | 0.73 | LMNA (0.43) | MEN1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL4735233 | 0.70 | KMT2A (0.57) | MEN1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL4737872 | 0.69 | KMT2A (0.51) | MEN1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL4736170 | 0.68 | KMT2A (0.58) | MEN1RAB9AKMT2AALDH1A1MAPT | |
| SCHEMBL4782112 | 0.68 | HCRTR1 (0.51) | MEN1RAB9AKMT2AGRIN2BALDH1A1 | |
| SCHEMBL4739350 | 0.67 | KMT2A (0.50) | MEN1RAB9AKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | claimed |
| WO-2008085008-A1 | T-CELL INHIBITING COMPOUNDS AND THEIR USE FOR THE TREATMENT OF T-CELL-MEDIATED DISEASES | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2008-07-17 | — | — | WO | disclosed |