Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740123 | 0.84 | CCR1 (0.47) | HTTALDH1A1POLBKMT2ANPSR1 | |
| SCHEMBL4741274 | 0.83 | TSHR (0.45) | MAPTHTTPOLBSMN1; SMN2LMNA | |
| SCHEMBL4740908 | 0.81 | P2RX7 (0.49) | MAPTHTTGAALMNANPSR1 | |
| SCHEMBL4740406 | 0.78 | ALDH1A1 (0.44) | HTTALDH1A1POLBGAALMNA | |
| SCHEMBL4741708 | 0.78 | ALDH1A1 (0.56) | ALDH1A1POLBGAAMEN1KMT2A | |
| SCHEMBL4739860 | 0.77 | ALDH1A1 (0.55) | ALDH1A1POLBGAASMN1; SMN2MEN1 | |
| SCHEMBL4740078 | 0.77 | GAA (0.50) | MAPTHTTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL4736653 | 0.75 | HSD11B1 (0.55) | ALDH1A1POLBGAA | |
| SCHEMBL4738964 | 0.75 | POLB (0.51) | MAPTHTTALDH1A1POLBGAA | |
| SCHEMBL4736650 | 0.75 | P2RX7 (0.53) | ALDH1A1GAASMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |