Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740908 | 0.86 | P2RX7 (0.49) | P2RX7HSD17B10CYP2C19LMNAUSP2 | |
| SCHEMBL4787137 | 0.84 | DPP4 (0.49) | HSD17B10CYP2C19LMNAL3MBTL1USP2 | |
| SCHEMBL4740078 | 0.81 | GAA (0.50) | CYP2C19LMNAUSP2GAASMN1; SMN2 | |
| SCHEMBL4736653 | 0.79 | HSD11B1 (0.55) | P2RX7GAAALDH1A1 | |
| SCHEMBL4738276 | 0.77 | CYP2C19 (0.52) | CYP2C19LMNAGAASMN1; SMN2KMT2A | |
| SCHEMBL4736655 | 0.77 | HSD17B10 (0.47) | HSD17B10CYP2C19LMNAUSP2GAA | |
| SCHEMBL4736709 | 0.77 | LMNA (0.57) | CYP2C19LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4737593 | 0.77 | LMNA (0.57) | CYP2C19LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL4740625 | 0.76 | LMNA (0.57) | CYP2C19LMNAL3MBTL1SMN1; SMN2ALDH1A1 | |
| SCHEMBL4737612 | 0.76 | LMNA (0.50) | HSD17B10CYP2C19LMNAUSP2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |