Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4736650 | 0.86 | P2RX7 (0.53) | P2RX7CYP2C19GAAHSD17B10LMNA | |
| SCHEMBL4787137 | 0.83 | DPP4 (0.49) | CYP2C19GAAHSD17B10LMNATSHR | |
| SCHEMBL4740078 | 0.82 | GAA (0.50) | CYP2C19GAATP53LMNAMAPT | |
| SCHEMBL4740404 | 0.81 | MAPT (0.47) | GAALMNAMAPTTSHRHTT | |
| SCHEMBL4740909 | 0.78 | CYP2C19 (0.46) | CYP2C19GAAHSD17B10USP2MAPK1 | |
| SCHEMBL4738276 | 0.77 | CYP2C19 (0.52) | CYP2C19GAALMNAMAPTNPSR1 | |
| SCHEMBL4736709 | 0.76 | LMNA (0.57) | CYP2C19TP53LMNAMAPTHTT | |
| SCHEMBL4737593 | 0.76 | LMNA (0.57) | CYP2C19TP53LMNAMAPTHTT | |
| SCHEMBL4740625 | 0.76 | LMNA (0.57) | CYP2C19LMNAMAPTTSHRHTT | |
| SCHEMBL4741708 | 0.75 | ALDH1A1 (0.56) | CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087654-A2 | PIPERIDINES AS INHIBITORS OF 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | CADILA HEALTHCARE LIMITED (IN) | 2008-07-24 | — | — | WO | claimed |