Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4742878 | 0.72 | POLB (0.49) | CRBNCHRNA3CHRNB4POLBKMT2A | |
| SCHEMBL28324714 | 0.72 | L3MBTL1 (0.46) | CHRNB2CHRNA4POLBKMT2A | |
| SCHEMBL21999450 | 0.71 | CHRNB2 (0.37) | CHRNB2CHRNA4CHRNA3CHRNB4 | |
| SCHEMBL6977466 | 0.70 | CRBN (0.53) | CRBNKMT2A | |
| SCHEMBL9078944 | 0.69 | POLB (0.57) | CRBNPOLBKMT2A | |
| SCHEMBL5347497 | 0.68 | CYP2D6 (0.39) | CHRNA3CHRNB4POLBKMT2A | |
| SCHEMBL1484948 | 0.68 | POLB (0.51) | CHRNB2CHRNA4CHRNA3CHRNB4POLB | |
| SCHEMBL30931485 | 0.68 | POLB (0.51) | CHRNB2CHRNA4CHRNA3CHRNB4POLB | |
| SCHEMBL1484949 | 0.68 | POLB (0.51) | CHRNB2CHRNA4CHRNA3CHRNB4POLB | |
| SCHEMBL13620123 | 0.68 | POLB (0.51) | CHRNB2CHRNA4CHRNA3CHRNB4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008093960-A1 | NOVEL DIPEPTIDYL PEPTIDASE-IV INHIBITORS | LG LIFE SCIENCES, LTD. (KR) | 2008-08-07 | — | — | WO | disclosed |