Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.54 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737623 | 0.88 | KDM4E (0.60) | LMNAALDH1A1MAPTKDM4ENTRK1 | |
| SCHEMBL4738310 | 0.84 | ALDH1A1 (0.71) | ALDH1A1MAPTKDM4ENTRK1NPC1 | |
| SCHEMBL14148402 | 0.82 | KDM4E (0.61) | LMNAALDH1A1MAPTKDM4EKCNK3 | |
| SCHEMBL4737640 | 0.78 | KDM4E (0.63) | ALDH1A1MAPTKDM4ENTRK1NPC1 | |
| SCHEMBL14148566 | 0.78 | ALDH1A1 (0.59) | LMNAALDH1A1MAPTKDM4ENTRK1 | |
| SCHEMBL6248559 | 0.78 | KDR (0.71) | LMNAALDH1A1MAPTKCNK3ADCY1 | |
| SCHEMBL4740897 | 0.78 | KDM4E (0.59) | LMNAALDH1A1MAPTKDM4ENTRK1 | |
| SCHEMBL4737628 | 0.77 | KDM4E (0.64) | ALDH1A1MAPTKDM4ENTRK1SMN1; SMN2 | |
| SCHEMBL14148528 | 0.76 | KDM4E (0.68) | ALDH1A1MAPTKDM4ENTRK1NPC1 | |
| SCHEMBL4737632 | 0.76 | KDM4E (0.62) | LMNAALDH1A1MAPTKDM4EKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090382-A1 | THIAZOLE AND OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF PRION DISEASES, CANCER AND CONDITIONS OF THE CENTRAL NERVOUS SYSTEM AS WELL AS IN THE REGULATION OF STEM CELLS | THE UNIVERSITY OF SHEFFIELD (GB) | 2008-07-31 | — | — | WO | disclosed |