Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4737623 | 0.81 | KDM4E (0.60) | KDM4EALDH1A1MAPTNTRK1GAA | |
| SCHEMBL14148405 | 0.81 | ALDH1A1 (0.67) | KDM4EALDH1A1MAPTNTRK1GAA | |
| SCHEMBL14148528 | 0.79 | KDM4E (0.68) | KDM4EALDH1A1MAPTNTRK1TP53 | |
| SCHEMBL4738310 | 0.79 | ALDH1A1 (0.71) | KDM4EALDH1A1MAPTNTRK1GAA | |
| SCHEMBL4740896 | 0.78 | LMNA (0.56) | KDM4EALDH1A1MAPTNTRK1GAA | |
| SCHEMBL4268936 | 0.77 | KDM4E (0.77) | KDM4EALDH1A1MAPTNTRK1GAA | |
| SCHEMBL4737640 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1MAPTNTRK1GAA | |
| SCHEMBL14148566 | 0.76 | ALDH1A1 (0.59) | KDM4EALDH1A1MAPTNTRK1GAA | |
| SCHEMBL14148384 | 0.74 | KDM4E (0.73) | KDM4EALDH1A1MAPTNTRK1GAA | |
| SCHEMBL4737628 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1MAPTNTRK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008090382-A1 | THIAZOLE AND OXAZOLE DERIVATIVES FOR USE IN THE TREATMENT OF PRION DISEASES, CANCER AND CONDITIONS OF THE CENTRAL NERVOUS SYSTEM AS WELL AS IN THE REGULATION OF STEM CELLS | THE UNIVERSITY OF SHEFFIELD (GB) | 2008-07-31 | — | — | WO | disclosed |