Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4741871 | 0.85 | HSD17B10 (0.42) | GSTO1MEN1KMT2AALDH1A1CNR1 | |
| SCHEMBL4741863 | 0.78 | GSTO1 (0.60) | GSTO1MEN1KMT2AALDH1A1PKM | |
| SCHEMBL840799 | 0.76 | CNR2 (0.57) | GSTO1MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL11177460 | 0.74 | PKM (0.58) | ALDH1A1KDM4ENPSR1PKMSMN1; SMN2 | |
| SCHEMBL22714740 | 0.73 | RECQL (0.48) | MEN1KMT2AALDH1A1KDM4ENPSR1 | |
| SCHEMBL19667171 | 0.73 | HSD17B10 (0.77) | MEN1KMT2AKDM4EPKMSMN1; SMN2 | |
| SCHEMBL4760475 | 0.72 | LMNA (0.74) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4739897 | 0.72 | ALDH1A1 (0.39) | GSTO1MEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL840686 | 0.72 | KMT2A (0.57) | GSTO1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL14100591 | 0.72 | GSTO1 (0.62) | GSTO1MEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008098025-A1 | ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |
| WO-2008098025-A1 | ARYLSULFONAMIDE COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-08-14 | — | — | WO | disclosed |