Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | MLYCD | O95822 | 2/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 6/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | PDCD4 | Q53EL6 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | FOS | P01100 | 1/20 | 0.42 |
| ▸ | JUN | P05412 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29158666 | 0.85 | TARBP2 (0.54) | MAPTKDM4EMEN1HSP90AA1CRHBP | |
| SCHEMBL1965950 | 0.85 | MEN1 (0.55) | MAPTKDM4EMEN1KMT2ATARBP2 | |
| SCHEMBL4738984 | 0.85 | GABRA2 (0.51) | MAPTKDM4ETARBP2PDCD4 | |
| SCHEMBL4742423 | 0.85 | TARBP2 (0.62) | MAPTKDM4EMEN1KMT2ATARBP2 | |
| SCHEMBL6365824 | 0.84 | TARBP2 (0.53) | MAPTKDM4EMEN1HSP90AA1CRHBP | |
| SCHEMBL29158606 | 0.84 | TARBP2 (0.63) | MAPTKDM4EMEN1HSP90AA1CRHBP | |
| SCHEMBL7701393 | 0.83 | TARBP2 (0.52) | MAPTKDM4EMEN1HSP90AA1CRHBP | |
| SCHEMBL4743899 | 0.83 | TARBP2 (0.64) | MAPTKDM4ETARBP2PDCD4 | |
| SCHEMBL29158788 | 0.83 | TARBP2 (0.66) | MAPTKDM4EMEN1HSP90AA1CRHBP | |
| SCHEMBL29158751 | 0.83 | TARBP2 (0.51) | MAPTKDM4EMEN1HSP90AA1CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008087611-A2 | PYRROLIDINE- AND PIPERIDINE- BIS-AMIDE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-07-24 | — | — | WO | disclosed |