SCHEMBL4599189

SCHEMBL4599189

NC(=O)N1CCC(O)CC1

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.38
DPP7 Q9UHL4 4/20 0.38
GPR119 Q8TDV5 1/20 0.37
GRM5 P41594 1/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
KDM1A O60341 1/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
GAA P10253 1/20 0.35
HTT P42858 2/20 0.35
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
LIPE Q05469 1/20 0.34
ATM Q13315 1/20 0.34
ALDH1A1 P00352 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
GRM3 Q14832 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2724587 0.85
SCHEMBL12669587 0.85
SCHEMBL16690584 0.85
Hydrochloric Acid SCHEMBL29766621 0.83 DPP4 (0.46) DPP4DPP7GRM5GAA
SCHEMBL2566319 0.81 KDM1A (0.37) NPC1KDM1AMAOAMAOBGAA
SCHEMBL4743328 0.81 KDM1A (0.37) GPR119KDM1AMAOAMAOBGAA
SCHEMBL14311848 0.80 DPP4 (0.36) DPP4DPP7GPR119GRM5NPC1
SCHEMBL1517004 0.79 GNAI3 (0.44) DPP4DPP7KDM1AMAOAMAOB
Sulfuric Acid SCHEMBL2306580 0.78 DPP4 (0.42) DPP4DPP7
SCHEMBL27785375 0.78 ALDH1A1 (0.46) DPP4DPP7GPR119GRM5NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116283920-B 2, 4-disubstituted pyridine compound and application thereof 贵州医科大学 2024-04-16 CN claimed
EP-4081507-B1 CHEMICAL COMPOUNDS TARGETING THE EYE AND USE THEREOF IN THE TREATMENT OF EYE DISEASES BIOPHYTIS (FR) 2023-11-22 EP claimed
CN-115335359-A Ocular targeting compounds and their use in treating ocular diseases 比奥菲蒂斯公司 2022-11-11 CN claimed
US-20220306674-A1 (2-ACETAMIDYL)THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2022-09-29 US claimed
US-20220280530-A1 PREVENTION OR TREATMENT OF DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE Anhui Newstar Pharmaceutical Development Co., Ltd. (CN) 2022-09-08 US claimed
CN-114728009-A Preventing or treating diseases and disorders associated with tissue damage 李晓祥 2022-07-08 CN claimed
CN-114206892-A (2-acetamido) thio-beta-D-galactopyranoside derivatives 爱杜西亚药品有限公司 2022-03-18 CN claimed
CN-114206893-A (hetero) aryl-methyl-thio-beta-D-galactopyranoside derivatives 爱杜西亚药品有限公司 2022-03-18 CN claimed
WO-2021130451-A1 CHEMICAL COMPOUNDS TARGETING THE EYE AND USE THEREOF IN THE TREATMENT OF EYE DISEASES BIOPHYTIS (FR) 2021-07-01 WO claimed
US-10975092-B2 Pyrimidine seven-membered-ring compounds, preparation method therefor, pharmaceutical composition thereof, and uses thereof ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) 2021-04-13 US claimed
US-20180312508-A1 PYRIMIDOPYRROLE COMPOUNDS, METHOD FOR PREPARING THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND USES THEREOF XIAMEN UNIVERSITY (CN) 2018-11-01 US claimed
EP-3290420-A1 PYRIMIDINE PYRROLE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USES THEREOF Xiamen University (CN) 2018-03-07 EP claimed
CN-101312724-A Tetrahydro-indazolyl cannabinoid modulators JANSSEN PHARMACEUTICA NV (BE) 2008-11-26 CN claimed
EP-1966194-A2 SUBSTITUTED 5-HETEROARYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA N.V. (BE) 2008-09-10 EP claimed
EP-1931336-A1 TETRAHYDRO-INDAZOLYL CANNABINOID MODULATORS Janssen Pharmaceutica, N.V. (BE) 2008-06-18 EP claimed
WO-2007061948-A2 SUBSTITUTED 5-HETEROARYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2007-05-31 WO claimed
US-20070117857-A1 Substituted 3-amido-tetrahydro-indazolyl cannabinoid modulators JANSSEN PHARMACEUTICA, N.V. 2007-05-24 US claimed
US-20070117858-A1 SUBSTITUTED 5-HETEROARYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2007-05-24 US claimed
WO-2007038045-A1 TETRAHYDRO-INDAZOLYL CANNABINOID MODULATORS JANSSEN PHARMACEUTICA, N.V. (BE) 2007-04-05 WO claimed
US-5688913-A OLIGOPEPTIDES AS ANTIINFLAMMATORY AGENTS CYTEL CORPORATION (US) 1997-11-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220306674-A1 (2-ACETAMIDYL)THIO-BETA-D-GALACTOPYRANOSIDE DERIVATIVES LGALS1, LGALS3, LGALS2 DPP4 131/4885DPP7 133/4885GPR119 247/4885
US-20180312508-A1 PYRIMIDOPYRROLE COMPOUNDS, METHOD FOR PREPARING THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND USES THEREOF TPMT, DHPS, TYMP DPP4 441/4885DPP7 532/4885GPR119 2445/4885
US-10975092-B2 Pyrimidine seven-membered-ring compounds, preparation method therefor, pharmaceutical composition thereof, and uses thereof MST1, STK11, MSTN DPP4 2507/4885DPP7 1791/4885GPR119 2915/4885
US-20070117857-A1 Substituted 3-amido-tetrahydro-indazolyl cannabinoid modulators CNR2, CNR1, GPR18 DPP4 3598/4885DPP7 3993/4885GPR119 17/4885
US-20220280530-A1 PREVENTION OR TREATMENT OF DISEASES AND DISORDERS ASSOCIATED WITH TISSUE DAMAGE MST1, MSTN, MST1R DPP4 3017/4885DPP7 2008/4885GPR119 2893/4885
US-20070117858-A1 SUBSTITUTED 5-HETEROARYL-1-PHENYL-PYRAZOLE CANNABINOID MODULATORS CNR1, CNR2, GPR18 DPP4 2965/4885DPP7 3837/4885GPR119 46/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.