Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746866 | 0.88 | HTT (0.48) | KMT2AMEN1SMN1; SMN2PKMMAPT | |
| SCHEMBL4788023 | 0.86 | TSHR (0.43) | KMT2AMEN1ALOX15MAPTCYP1A2 | |
| SCHEMBL4746067 | 0.86 | KMT2A (0.46) | KMT2AMEN1ALOX15MAPTCYP1A2 | |
| SCHEMBL4743021 | 0.85 | ALDH1A1 (0.42) | KMT2AMEN1SMN1; SMN2ALOX15MAPT | |
| SCHEMBL4784226 | 0.85 | KMT2A (0.46) | KMT2AMEN1SMN1; SMN2ALOX15MAPT | |
| SCHEMBL8161152 | 0.84 | TP53 (0.45) | KMT2AMEN1SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL4786646 | 0.81 | AKR1C3 (0.41) | KMT2AMEN1PKMMAPK1ALDH1A1 | |
| SCHEMBL4745419 | 0.81 | MCOLN3 (0.46) | KMT2AMEN1CYP3A4CYP2C19MCOLN3 | |
| SCHEMBL4785277 | 0.80 | KMT2A (0.42) | KMT2AMEN1SMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL8153861 | 0.79 | ACLY (0.45) | KMT2AMEN1SMN1; SMN2ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |