Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746102 | 0.88 | ACLY (0.44) | KMT2AMEN1MAPTTHRBCYP1A2 | |
| SCHEMBL4805415 | 0.86 | KMT2A (0.49) | KMT2AMEN1MAPTTHRBCYP1A2 | |
| SCHEMBL4746067 | 0.85 | KMT2A (0.46) | KMT2AMEN1MAPTTHRBCYP1A2 | |
| SCHEMBL4745419 | 0.84 | MCOLN3 (0.46) | KMT2AMEN1CYP3A4CYP2C19 | |
| SCHEMBL8153861 | 0.83 | ACLY (0.45) | KMT2AMEN1MAPTTHRBCYP1A2 | |
| SCHEMBL4788750 | 0.82 | HSD11B1 (0.47) | KMT2AMEN1MAPTTHRBCYP1A2 | |
| SCHEMBL4746895 | 0.81 | MAPT (0.49) | KMT2AMEN1MAPTRECQLTP53 | |
| SCHEMBL4787200 | 0.80 | TSHR (0.43) | KMT2AALOX15POLB | |
| SCHEMBL4743057 | 0.79 | ALDH1A1 (0.47) | KMT2ARECQLPOLB | |
| SCHEMBL8161152 | 0.79 | TP53 (0.45) | KMT2AMEN1MAPTTHRBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115259-A2 | DERIVATIVES OF BENZOXADIAZOLE SUITABLE FOR THE TREATMENT OF CELL PROLIFERATIVE DISEASES | RIGEL PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | WO | claimed |