Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 14/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750004 | 0.82 | GRM2 (0.39) | GRM2ALDH1A1KDM4E | |
| SCHEMBL4747299 | 0.79 | GRM2 (0.38) | GRM2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4747767 | 0.75 | GRM2 (0.37) | GRM2 | |
| SCHEMBL4750023 | 0.74 | HSF1 (0.41) | GRM2ALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL5815996 | 0.73 | ALDH1A1 (0.37) | GRM2ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL4747715 | 0.73 | PDE2A (0.37) | GRM2ALDH1A1 | |
| SCHEMBL4750217 | 0.72 | PDE2A (0.37) | GRM2ALDH1A1 | |
| SCHEMBL10232910 | 0.71 | KDM4E (0.41) | GRM2ALDH1A1KDM4EMAPT | |
| SCHEMBL4750623 | 0.70 | GRM2 (0.40) | GRM2ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4788109 | 0.68 | MAPK9 (0.44) | ALDH1A1SMN1; SMN2KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123755-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTAM TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |
| WO-2008123755-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTAM TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | disclosed |