Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSF1 | Q00613 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750004 | 0.76 | GRM2 (0.39) | ALDH1A1KDM4EGRM2PKM | |
| SCHEMBL5815996 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL4747263 | 0.74 | GRM2 (0.36) | ALDH1A1KDM4EMAPTGRM2MEN1 | |
| SCHEMBL4747299 | 0.73 | GRM2 (0.38) | ALDH1A1KDM4EHPGDGRM2HSD17B10 | |
| SCHEMBL4788109 | 0.72 | MAPK9 (0.44) | ALDH1A1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL4747767 | 0.69 | GRM2 (0.37) | GRM2 | |
| SCHEMBL4747715 | 0.68 | PDE2A (0.37) | ALDH1A1GRM2POLBADORA2AADORA1 | |
| SCHEMBL3455186 | 0.67 | ADORA2A (0.48) | ADORA2BADORA2AADORA1 | |
| SCHEMBL4750217 | 0.67 | PDE2A (0.37) | ALDH1A1GRM2POLBADORA1MAT2A | |
| SCHEMBL10232910 | 0.66 | KDM4E (0.41) | ALDH1A1KDM4EMAPTGAAGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008123755-A1 | A PHARMACEUTICAL COMPOSITIONS CONTAINING LACTAM TYPE PYRIDINE DERIVATIVES AS AN EFFECTIVE INGREDIENT FOR THE PREVENTION AND TREATMENT OF ISCHEMIA | SK CHEMICALS CO., LTD. (KR) | 2008-10-16 | — | — | WO | claimed |