Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750958 | 0.85 | VEGFA (0.42) | FAAHALDH1A1KDM4E | |
| SCHEMBL4749778 | 0.84 | LTA4H (0.41) | KMT2ALTA4HALDH1A1KDM4EMEN1 | |
| SCHEMBL4750459 | 0.83 | LTA4H (0.41) | LTA4HALDH1A1KDM4ELMNASIGMAR1 | |
| SCHEMBL4788759 | 0.83 | LTA4H (0.40) | KMT2ALTA4HALDH1A1KDM4EMEN1 | |
| SCHEMBL4747133 | 0.83 | LTA4H (0.42) | KMT2ALTA4HALDH1A1KDM4EMEN1 | |
| Ammonia Solution, Strong SCHEMBL4788727 | 0.82 | LTA4H (0.41) | LTA4HALDH1A1KDM4ELMNASIGMAR1 | |
| SCHEMBL4749740 | 0.80 | KMT2A (0.41) | FAAHKMT2ATSHRAIMP2LTA4H | |
| SCHEMBL211923 | 0.76 | FAAH (0.72) | FAAHKMT2ATSHRALDH1A1KDM4E | |
| SCHEMBL3085198 | 0.70 | FAAH (0.48) | FAAHKMT2AALDH1A1KDM4ELMNA | |
| SCHEMBL4746893 | 0.69 | ALDH1A1 (0.47) | TSHRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130319-A2 | NOVEL N-TETRAHYDRONAPHTALENE OR N-CHROMANE CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | disclosed |