Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788759 | 0.99 | LTA4H (0.40) | LTA4HALDH1A1KDM4EPOLBADRA2A | |
| SCHEMBL4747133 | 0.99 | LTA4H (0.42) | LTA4HALDH1A1KDM4EPOLBADRA2A | |
| SCHEMBL4750459 | 0.88 | LTA4H (0.41) | LTA4HALDH1A1KDM4EPOLBCHRNA7 | |
| Ammonia Solution, Strong SCHEMBL4788727 | 0.87 | LTA4H (0.41) | LTA4HALDH1A1KDM4EPOLBCHRNA7 | |
| SCHEMBL4747555 | 0.84 | FAAH (0.46) | LTA4HALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4750958 | 0.79 | VEGFA (0.42) | ALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL4788563 | 0.76 | DRD3 (0.42) | ALDH1A1POLBADRA2AADRA2BADRA2C | |
| SCHEMBL4788569 | 0.76 | DRD3 (0.42) | ALDH1A1POLBADRA2AADRA2BADRA2C | |
| Ammonia Solution, Strong SCHEMBL4789081 | 0.76 | TDP1 (0.46) | LTA4HALDH1A1KDM4EPOLB | |
| SCHEMBL4788900 | 0.74 | CXCR3 (0.43) | LTA4HMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130319-A2 | NOVEL N-TETRAHYDRONAPHTALENE OR N-CHROMANE CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | disclosed |