Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747811 | 0.97 | CACNA1G (0.43) | CACNA1GLMNAPOLBXBP1HTT | |
| SCHEMBL4747842 | 0.97 | CACNA1G (0.43) | CACNA1GLMNAPOLBXBP1HTT | |
| SCHEMBL4913486 | 0.91 | MEN1 (0.43) | CACNA1GLMNAHTTOPRL1MEN1 | |
| SCHEMBL4744706 | 0.90 | CACNA1G (0.41) | CACNA1GLMNAHTTHTR2AHTR2C | |
| SCHEMBL4748756 | 0.88 | MEN1 (0.47) | CACNA1GLMNAHTTSMN1; SMN2OPRL1 | |
| SCHEMBL4744227 | 0.88 | MEN1 (0.42) | CACNA1GLMNAHTTOPRL1MEN1 | |
| SCHEMBL4744345 | 0.87 | CACNA1G (0.43) | CACNA1GLMNAHTTHTR2AHTR2C | |
| SCHEMBL4748785 | 0.87 | CACNA1G (0.43) | CACNA1GLMNAHTTSMN1; SMN2HTR2A | |
| SCHEMBL4744647 | 0.87 | KDM4E (0.40) | CACNA1GLMNAHTTHTR2AHTR2C | |
| SCHEMBL4747027 | 0.87 | ALDH1A1 (0.40) | CACNA1GLMNAHTTSMN1; SMN2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | claimed |