Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14004473 | 1.00 | SNCA (0.44) | SNCAALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL4748284 | 1.00 | SNCA (0.44) | SNCAALDH1A1KDM4ELMNAL3MBTL1 | |
| SCHEMBL4749293 | 0.79 | ACHE (0.43) | SNCAALDH1A1MAPTPOLBNAMPT | |
| Hydrochloric Acid SCHEMBL4889022 | 0.78 | ACHE (0.42) | SNCAALDH1A1MAPTPOLBKMT2A | |
| SCHEMBL4889055 | 0.78 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1SMN1; SMN2POLBMEN1 | |
| SCHEMBL4898157 | 0.69 | ALDH1A1 (0.50) | ALDH1A1KDM4EMAPTMAPK1SMN1; SMN2 | |
| SCHEMBL7487919 | 0.67 | ESR1 (0.53) | SNCAALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL2215434 | 0.66 | L3MBTL1 (0.60) | ALDH1A1KDM4EL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL2215429 | 0.66 | L3MBTL1 (0.60) | ALDH1A1KDM4EL3MBTL1MAPTSMN1; SMN2 | |
| SCHEMBL7958886 | 0.65 | AGER (0.47) | NAMPTACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | METASTATIX, INC. | 2008-11-27 | — | — | US | disclosed |
| WO-2008112156-A1 | CHEMOKINE RECEPTOR MODULATORS | ALTIRIS THERAPEUTICS (US) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293711-A1 | Chemokine receptor modulators | CCR5, CCL2, CXCR4 | SNCA 4858/4885ALDH1A1 1359/4885KDM4E 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.