Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3414187 | 0.86 | BRD4 (0.49) | ARKRASMAPTSMN1; SMN2NPC1 | |
| SCHEMBL18917851 | 0.83 | BRD4 (0.51) | ARKRASMAPTSMN1; SMN2NPC1 | |
| SCHEMBL2943033 | 0.82 | BRD4 (0.40) | MAPK1BRD4MTNR1AMTNR1B | |
| SCHEMBL2948637 | 0.81 | CYP2A6 (0.44) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL2951656 | 0.80 | DRD2 (0.40) | DRD2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL9541765 | 0.79 | HTR7 (0.46) | ARKRASMAPTSMN1; SMN2LMNA | |
| SCHEMBL2941157 | 0.77 | PLG (0.45) | ARKRASMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8545929 | 0.75 | KRAS (0.47) | ARKRASMAPTNPC1RAB9A | |
| SCHEMBL15522269 | 0.74 | ALDH1A1 (0.48) | KRASMAPTDRD2ALDH1A1LMNA | |
| SCHEMBL31735444 | 0.73 | MEN1 (0.46) | ARKRASMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132162-A1 | 3- (SULPHONYLAMINO) -PHENYL-2 -HYDROXY-ETHYLAMINO DERIVATIVES USEFUL AS BETA-AGONISTS, PROCESSES FOR PREPARING THEM AND THEIR USE AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-11-06 | — | — | WO | disclosed |