Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TERT | O14746 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748864 | 0.94 | ALDH1A1 (0.68) | LMNAALDH1A1POLBKMT2ATERT | |
| SCHEMBL14041580 | 0.89 | POLB (0.63) | LMNAALDH1A1POLBKMT2ATERT | |
| SCHEMBL14041496 | 0.87 | KMT2A (0.60) | LMNAALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL4748462 | 0.86 | ALDH1A1 (0.62) | LMNAALDH1A1POLBKMT2ASMN1; SMN2 | |
| SCHEMBL4749787 | 0.83 | ALOX5 (0.57) | LMNAALDH1A1POLBKMT2ATERT | |
| SCHEMBL4750226 | 0.83 | KMT2A (0.71) | LMNAALDH1A1POLBKMT2ATERT | |
| SCHEMBL8227510 | 0.82 | ALDH1A1 (0.83) | LMNAALDH1A1POLBKMT2ACYP2C19 | |
| SCHEMBL4749305 | 0.81 | TERT (0.63) | LMNAALDH1A1POLBKMT2ATERT | |
| Water SCHEMBL7291985 | 0.81 | ALDH1A1 (0.81) | LMNAALDH1A1POLBKMT2ACYP2C19 | |
| SCHEMBL14041773 | 0.80 | EPHX2 (0.59) | LMNAALDH1A1POLBKMT2ATERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |