Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | CSF1R | P07333 | 6/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752089 | 0.79 | EGFR (0.53) | EGFRCSF1RGRM4MAPTRAB9A | |
| SCHEMBL4748557 | 0.75 | MAP2K1 (0.48) | EGFRCSF1RGRM4MCHR1MAP2K1 | |
| SCHEMBL4748744 | 0.75 | EGFR (0.39) | EGFRCSF1RGRM4MAPTRAB9A | |
| SCHEMBL4748555 | 0.72 | MAPT (0.40) | EGFRCSF1RGRM4MAPTHDAC6 | |
| SCHEMBL14022253 | 0.71 | RAPGEF4 (0.48) | EGFRCSF1RGRM4MAPTERBB2 | |
| SCHEMBL13529659 | 0.67 | MAP2K1 (0.52) | EGFRCSF1RGRM4MAPTMAP2K1 | |
| SCHEMBL4786865 | 0.63 | CSF1R (0.43) | CSF1RGRM4MCHR1MAPTRAB9A | |
| SCHEMBL31366880 | 0.62 | MAPT (0.54) | MAPTRAB9ANPC1SMN1; SMN2MAP2K1 | |
| SCHEMBL6553046 | 0.61 | HSD17B2 (0.56) | RAB9AHDAC6SMN1; SMN2 | |
| SCHEMBL17396634 | 0.61 | EGFR (0.51) | EGFRGRM4MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008132464-A2 | MEK5 AND RELATED PROTEINS AS BIOMARKERS OF NEURODEGENERATIVE DISEASES | THE UNIVERSITY OF NOTTINGHAM (GB) | 2008-11-06 | — | — | WO | disclosed |