Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SDCBP | O00560 | 1/20 | 0.31 |
| ▸ | SDC2 | P34741 | 1/20 | 0.31 |
| ▸ | OXTR | P30559 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | MC4R | P32245 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746505 | 1.00 | HSD11B1 (0.39) | HSD11B1PIK3CGKCNH2PIK3CDPIK3R1 | |
| SCHEMBL4746488 | 0.82 | HSD11B1 (0.39) | HSD11B1KCNH2SIGMAR1OPRM1 | |
| SCHEMBL4746487 | 0.82 | HSD11B1 (0.39) | HSD11B1KCNH2SIGMAR1OPRM1 | |
| SCHEMBL4746540 | 0.78 | IDO1 (0.34) | HSD11B1SIGMAR1OPRM1 | |
| SCHEMBL4746538 | 0.78 | IDO1 (0.34) | HSD11B1SIGMAR1OPRM1 | |
| SCHEMBL4746032 | 0.72 | P2RX7 (0.39) | — | |
| SCHEMBL22440916 | 0.72 | PIK3CG (0.54) | PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL22440915 | 0.72 | PIK3CG (0.54) | PIK3CGPIK3CDPIK3R1 | |
| SCHEMBL2023945 | 0.71 | PIK3CG (0.50) | HSD11B1PIK3CGKCNH2PIK3CDPIK3R1 | |
| SCHEMBL2019136 | 0.71 | PIK3CG (0.50) | HSD11B1PIK3CGKCNH2PIK3CDPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124518-A1 | OXO-DIHYDROISOINDOLE SULFONAMIDE COMPOUNDS AS MODULATORS OF THE CCK2 RECEPTOR | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-10-16 | — | — | WO | disclosed |