Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749201 | 0.84 | MEN1 (0.44) | MEN1KMT2AMAPK1POLBHDAC4 | |
| SCHEMBL4749102 | 0.74 | POLB (0.36) | MEN1KMT2APOLBHDAC4TSHR | |
| SCHEMBL4749101 | 0.72 | POLB (0.38) | MEN1KMT2APOLBTSHR | |
| SCHEMBL4749099 | 0.72 | POLB (0.38) | MEN1KMT2APOLBTSHR | |
| SCHEMBL4749058 | 0.71 | EED (0.37) | KMT2AMAPK1POLBTSHR | |
| SCHEMBL4749061 | 0.71 | EED (0.37) | KMT2AMAPK1POLBTSHR | |
| SCHEMBL4752708 | 0.69 | MEN1 (0.43) | MEN1KMT2AMAPK1 | |
| SCHEMBL4752869 | 0.65 | MEN1 (0.40) | MEN1KMT2AMAPK1 | |
| SCHEMBL4751351 | 0.65 | MEN1 (0.40) | MEN1KMT2AMAPK1 | |
| SCHEMBL4749182 | 0.65 | MGLL (0.39) | MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |