Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 4/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751351 | 1.00 | MEN1 (0.40) | MEN1KMT2AOPRM1MAPK1MGLL | |
| SCHEMBL4749392 | 0.92 | MGLL (0.36) | MEN1KMT2AOPRM1MGLL | |
| SCHEMBL4018836 | 0.91 | GRIN1 (0.38) | MEN1KMT2AMAPK1MGLL | |
| SCHEMBL4749224 | 0.88 | OPRM1 (0.35) | MEN1KMT2AOPRM1MAPK1MGLL | |
| SCHEMBL4749242 | 0.88 | OPRM1 (0.35) | MEN1KMT2AOPRM1MAPK1MGLL | |
| SCHEMBL4022030 | 0.88 | MEN1 (0.34) | MEN1KMT2AOPRM1MAPK1MGLL | |
| SCHEMBL4021646 | 0.88 | MC4R (0.36) | MEN1KMT2AOPRM1MGLL | |
| SCHEMBL4749182 | 0.87 | MGLL (0.39) | MEN1KMT2AMAPK1MGLL | |
| SCHEMBL4805388 | 0.87 | MGLL (0.39) | MEN1KMT2AMAPK1MGLL | |
| SCHEMBL4751652 | 0.87 | MGLL (0.39) | MEN1KMT2AMAPK1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |