Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749651 | 0.89 | KDM4E (0.54) | MAPTLMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL4749247 | 0.81 | MAPT (0.48) | MAPTLMNAPTPN2ALDH1A1TSHR | |
| SCHEMBL4738274 | 0.77 | MAPT (0.45) | MAPTLMNAALDH1A1TSHRTDP1 | |
| SCHEMBL4751445 | 0.76 | L3MBTL1 (0.58) | MAPTLMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL4783860 | 0.75 | MAPT (0.48) | MAPTLMNAALDH1A1TDP1L3MBTL1 | |
| SCHEMBL4752200 | 0.73 | RAB9A (0.52) | MAPTLMNAPTPN2PTPRBPTPN6 | |
| SCHEMBL934157 | 0.72 | TSHR (0.54) | MAPTLMNAALDH1A1TSHRTDP1 | |
| SCHEMBL11564640 | 0.72 | LMNA (0.51) | MAPTLMNAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL30216449 | 0.70 | ALDH1A1 (0.57) | MAPTLMNAPTPN2PTPRBPTPN6 | |
| SCHEMBL4326021 | 0.70 | ALDH1A1 (0.47) | MAPTLMNAALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140214-A1 | USE OF AMINOTHIOPHENE DERIVATIVE FOR PREVENTING OR TREATING ISCHEMIC DISEASES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | disclosed |