Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | HTR1F | P30939 | 1/20 | 0.34 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018836 | 0.95 | GRIN1 (0.38) | MGLLKMT2AMEN1HTR1FKDM2B | |
| SCHEMBL4752869 | 0.92 | MEN1 (0.40) | MGLLKMT2AMEN1OPRM1 | |
| SCHEMBL4751351 | 0.92 | MEN1 (0.40) | MGLLKMT2AMEN1OPRM1 | |
| SCHEMBL4752848 | 0.90 | KDM4E (0.37) | MGLLKMT2AMEN1HTR1FGRIN1 | |
| SCHEMBL4022671 | 0.89 | NPSR1 (0.39) | MGLLKMT2AMEN1KDM2B | |
| SCHEMBL4021759 | 0.89 | MGLL (0.39) | MGLLOPRM1GRIN1GRIN2B | |
| SCHEMBL4021748 | 0.89 | MGLL (0.39) | MGLLOPRM1GRIN1GRIN2B | |
| SCHEMBL4023652 | 0.88 | MGLL (0.39) | MGLLGRIN1GRIN2B | |
| SCHEMBL4023633 | 0.88 | MGLL (0.39) | MGLLGRIN1GRIN2B | |
| SCHEMBL4752891 | 0.87 | ABL1 (0.37) | MGLLKMT2AMEN1OPRM1KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |