Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ABL2 | P42684 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.35 |
| ▸ | ESRRG | P62508 | 5/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 2/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 3/20 | 0.33 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018836 | 0.90 | GRIN1 (0.38) | KDM2BMGLLMEN1KMT2AGRIN1 | |
| SCHEMBL4020633 | 0.90 | MEN1 (0.35) | KDM2BESRRGOPRM1OPRD1OPRK1 | |
| SCHEMBL4025711 | 0.89 | DRD2 (0.32) | ABL1EGFRLCKSRCABL2 | |
| SCHEMBL4752161 | 0.88 | KDM2B (0.33) | ABL1EGFRLCKSRCABL2 | |
| SCHEMBL4749392 | 0.87 | MGLL (0.36) | KDM2BOPRM1MGLLMEN1KMT2A | |
| SCHEMBL4751303 | 0.86 | KDM2B (0.33) | KDM2BESRRGMGLLMEN1KMT2A | |
| SCHEMBL4752190 | 0.85 | KDM2B (0.34) | ABL1EGFRSRCABL2KDM2B | |
| SCHEMBL4021646 | 0.85 | MC4R (0.36) | KDM2BESRRGOPRM1OPRD1MGLL | |
| SCHEMBL4752848 | 0.85 | KDM4E (0.37) | ESRRGMGLLHTR1AMEN1KMT2A | |
| SCHEMBL4752869 | 0.85 | MEN1 (0.40) | OPRM1MGLLMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |