Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 6/20 | 0.37 |
| ▸ | HTR1F | P30939 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749392 | 0.95 | MGLL (0.36) | GRIN1GRIN2BMGLLHTR1FKMT2A | |
| SCHEMBL4752848 | 0.94 | KDM4E (0.37) | GRIN1GRIN2BMGLLHTR1FKMT2A | |
| SCHEMBL4752869 | 0.91 | MEN1 (0.40) | MGLLKMT2AMEN1MAPK1 | |
| SCHEMBL4751351 | 0.91 | MEN1 (0.40) | MGLLKMT2AMEN1MAPK1 | |
| SCHEMBL4752891 | 0.90 | ABL1 (0.37) | GRIN1GRIN2BMGLLKMT2AMEN1 | |
| SCHEMBL4021646 | 0.89 | MC4R (0.36) | GRIN1GRIN2BMGLLKMT2AMEN1 | |
| SCHEMBL4022170 | 0.89 | NPSR1 (0.42) | GRIN1GRIN2BMGLLKMT2AMEN1 | |
| SCHEMBL4025296 | 0.88 | MGLL (0.35) | GRIN1GRIN2BMGLLKMT2AMEN1 | |
| SCHEMBL4022812 | 0.88 | HTR6 (0.35) | MGLLKDM2B | |
| SCHEMBL4022671 | 0.88 | NPSR1 (0.39) | MGLLKMT2AMEN1KDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |